![]() 2, 3 Similar to other conditions and other targets, variability in outcomes remains, and the underpinning of such variability remains incompletely understood. 1 Successful motor symptom reduction has been validated in randomized clinical trials with DBS of the GPi. Globus pallidus internus (GPi) deep brain stimulation (DBS) is an established treatment for Parkinson disease (PD). ABBREVIATIONS: DBS deep brain stimulation FGATIR fast gray matter acquisition T1 inversion recovery GPe globus pallidus externus GPi globus pallidus internus M1 primary motor cortex MNI Montreal Neurological Institute PD Parkinson disease SMA/PMC supplementary motor area/premotor cortex SN substantia nigra STN subthalamic nucleus UPDRS III Unified Parkinson Disease Rating Scale, Part III VTA volume of tissue activated ![]()
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